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What causes erectile dysfunction (ED)?

Over 400 million men worldwide are affected by ED.1 Find out the common causes.

You wouldn’t be the only one to ever wonder “why me?” But if you’re still searching for answers, knowing the physiology behind erections and the common causes of ED may help you understand your experience. However, only a doctor will be able to offer a true diagnosis.

Erection and ejaculation are influenced by many factors that work together, including2:

  • Vasculogenic factors
  • Neurogenic factors
  • Endocrinologic factors
  • Trauma
  • Medications
  • Obesity
  • Sedentary lifestyle
  • Alcohol use
  • Tobacco use

ED can result from a disruption in many of the body's processes. That is why the following situations have been commonly associated with erectile dysfunction3:

  • Diabetes, which can damage the nerves or blood vessels that control blood flow to the penis
  • Cardiovascular problems, which can include blocked arteries or leaking veins that decrease blood flow to the penis
  • Trauma or surgery in the prostate, bladder, colon or rectal area, which can damage nerves
  • Spinal cord injuries, which can stop nerve impulses from reaching the penis
  • Medications, including some for high blood pressure and depression, which can interfere with blood flow to the penis
  • Hormone problems caused by kidney or liver failure

9 times out of 10

the cause of ED is physical, and it can be an indication of overall health in one’s body.3

  1. Market research data on file, American Medical Systems.
  2. Seftel A. Challenges in oral therapy for erectile dysfunction. J Androl. 2002;23:729-736.
  3. Goldstein I. Working Group for the Study of Central Mechanisms in Erectile Dysfunction. Male sexual circuitry. Sci Am. 2000;283(2):70-75.